Type 2 Diabetes
rxfiles.ca/diabetes
Our comprehensive guide to the management of Type 2 Diabetes Mellitus, with a focus on optimizing drug therapy.
Our comprehensive guide to the management of Type 2 Diabetes Mellitus, with a focus on optimizing drug therapy.
Introduction
page 2
Welcome to the third edition of RxFiles: Type 2 Diabetes.
page 3
A collection of learnings, pearls, and things that may surprise you.
page 4
How to screen for T2DM, risk factors for T2DM, diagnosis tree, and an approach to T2DM therapy
page 5
A guide to individualizing glycemic targets for your patient.
page 6
Guidelines and FAQs for blood pressure, lipids, ACEI/ARB, ASA, and lifestyle change.
page 7
Lifestyle change: the best available treatment for type 2 diabetes.
page 8
A guide to protecting and preserving the kidneys in diabetes.
page 9
A guide to comanaging patients with both diabetes and heart failure.
page 10
A guide to managing pregnant patients with diabetes.
page 11
A guide to managing older adults with diabetes.
page 12
Key messages for using pharmacotherapy in diabetes.
page 13
Metformin: first-line, and the backbone of pharmacotherapy.
page 14
Efficacy, indications, adverse effects, contraindications, drug interactions, monitoring parameters, dosing, and cost comparisons of diabetes pharmacotherapy.
page 17
Efficacy, indications, adverse effects, contraindications, drug interactions, monitoring parameters, dosing, and cost comparisons of weight loss pharmacotherapy.
page 18
Side-by-side comparisons of diabetes pharmacotherapy using a 'traffic light' approach.
page 20
Common, less common, rare, and uncertain adverse effects of GLP1 agonists.
page 21
Common, less common, rare, and uncertain adverse effects of SGLT2 inhibitors.
page 22
Key messages for using insulin in diabetes.
page 23
Compares and lists the different disposable and reusable insulin pens.
page 24
Side-by-side comparisons of the different BASAL and PRANDIAL insulins available.
page 26
How to initiate insulin, injection tips and common mistakes, troubleshooting titration, converting between insulins, using insulin to treat corticosteroid hyperglycemia, and travel tips.
page 28
Treating hypoglcyemia, glucagon drug info, and diabetes 'sick day' guidelines.
page 29
How to assess and address a patient's risk of hypoglycemia.
page 30
Guidance on how often patients should self monitor blood glucose, and a comparison of available blood glucose meters.
page 31
Comparison of basal insulins by cost, coverage, convenience, and hypoglycemia.
page 32
An overview of the diabetes tools in this book.
page 33
A user-friendly approach to helping patients decide which diabetes therapy might be best for them.
page 35
Optimizing the choice and use of insulin needles.
page 36
Evidence suggests that prescribing physical activity is more powerful than simply talking to patients about it.
page 37
A handout guiding patients how to pause, and when to restart, medications that can cause acute kidney injury or other side effects when patients are dehydrated.
A patient booklet for patients with type 2 diabetes, designed to motivate patients to exercise, take their medications regularly, test their sugars only when needed, inject insulin properly, and hold SADMANS medications when dehydrated.
page 38
An overview of the landmark diabetes trials collected here.
page 39
Describes the population studied, intervention, A1c achieved, and macrovascular outcomes of landmark diabetes cardiovascular outcome trials.
page 40
Describes the population studied, intervention, A1c achieved, microvascular outcomes, and macrovascular outcomes of landmark glycemic target trials.
page 41
Describes the population studied, intervention, efficacy outcomes, and safety outcomes of landmark insulin trials.
page 42
Describes the population studied, intervention, and results of landmark lipid, ASA, blood pressure, and diabetes prevention trials.
page 44
Thank you to everyone who helped with the creation of this book!
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