rxfiles.ca/trials
We undertake a lot of critical appraisal to create our drug comparison charts. Selected insight from that appraisal is published here.
FIGARO-DKD
Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease
2021
MICRO-HOPE
The Effects of Ramipril on Cardiovascular & Microvascular Outcomes in those with T2DM
2000
EMPA-KIDNEY
Empagliflozin 10mg vs Placebo in Patients
with Chronic Kidney Disease, with or without Type 2 Diabetes
2023
CONFIDENCE
The Effect of Simultaneous Initiation of Finerenone with Empagliflozin
on UACR in CKD and T2DM
2025
MICRO-HOPE
The Effects of Ramipril on Cardiovascular and Microvascular Outcomes in those with T2DM
2000
Delayed Antibiotics for Children with Respiratory Infections
Effectiveness & safety of delayed vs immediate vs no
antibiotic prescription in children with uncomplicated respiratory tract infections
2021
FINEARTS-HF
Finerenone vs placebo in patients with mildly reduced or preserved ejection fraction.
2024
Medication Overuse Headache Management
Withdrawal, prophylaxis, or both for the management of medication overuse headache.
Effect of High-Dose Vit D on Bone Density & Strength
Vitamin D 400 units vs 4,000 units vs 10,000 units in primary prevention of osteoporosis.
PIONEER AF-PCI
Rivaroxaban + P2Y12 inhibitor vs rivaroxaban + DAPT vs warafrin + DAPT in a-fib & PCI.
Amoxicillin vs Placebo for Respiratory Tract Infections
Amoxicillin versus placebo in patients with acute lower-respiratory-tract infection
in primary care when pneumonia is not suspected
(e.g. bronchitis)
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